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Cellosaurus CHO-DXB11 hGCR SC 12.9 (CVCL_C1CN)

[Text version]
Cell line name CHO-DXB11 hGCR SC 12.9
Synonyms Subclone 12.9
Accession CVCL_C1CN
Resource Identification Initiative To cite this cell line use: CHO-DXB11 hGCR SC 12.9 (RRID:CVCL_C1CN)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4177; GBA1 (Note=With p.Arg534His).
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=23091360; DOI=10.1155/2012/875383; PMCID=PMC3471063
Novo J.B., Morganti L., Moro A.M., Paes Leme A.F., de Toledo Serrano S.M., Raw I., Ho P.L.
Generation of a Chinese hamster ovary cell line producing recombinant human glucocerebrosidase.
J. Biomed. Biotechnol. 2012:875383.1-875383.10(2012)

Cross-references
Encyclopedic resources Wikidata; Q114310948
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7