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Cellosaurus RPE1_APC_836 (CVCL_C1AM)

[Text version]
Cell line name RPE1_APC_836
Accession CVCL_C1AM
Resource Identification Initiative To cite this cell line use: RPE1_APC_836 (RRID:CVCL_C1AM)
Comments Part of: Cancer Pathway Knockout Panel.
Knockout cell: Method=CRISPR/Cas9; HGNC; 583; APC.
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4388 (hTERT-RPE1)
Sex of cell Female
Age at sampling 1Y
Category Telomerase immortalized cell line
Publications

PubMed=35692635; DOI=10.1016/j.isci.2022.104437
Cook A.L., Wyhs N., Sur S., Ptak B., Popoli M., Dobbyn L., Papadopoulos T., Bettegowda C., Papadopoulos N., Vogelstein B., Zhou S.-B., Kinzler K.W.
An isogenic cell line panel for sequence-based screening of targeted anticancer drugs.
IScience 25:104437.1-104437.14(2022)

Cross-references
Encyclopedic resources Wikidata; Q114312816
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5