ID   PCI-03
AC   CVCL_C169
SY   PCI-3
DR   BioSample; SAMN03151894
DR   cancercelllines; CVCL_C169
DR   Wikidata; Q54938648
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RX   PubMed=2766286;
RX   PubMed=17312569;
RX   PubMed=21868764;
CC   Problematic cell line: Contaminated. Shown to be a PC-3 derivative (PubMed=21868764). Originally thought to originate from a 50 year old male patient with a retromolar trigone squamous cell carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00420.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
ST   Source(s): PubMed=21868764
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 11
ST   D5S818: 13
ST   D7S820: 8,11
ST   TH01: 7
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 23
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RA   Carey T.E.;
RT   "Head and neck tumor cell lines.";
RL   (In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994).
RX   PubMed=2766286;
RA   Heo D.S., Snyderman C.H., Gollin S.M., Pan S., Walker E., Deka R.,
RA   Barnes E.L., Johnson J.T., Herberman R.B., Whiteside T.L.;
RT   "Biology, cytogenetics, and sensitivity to immunological effector
RT   cells of new head and neck squamous cell carcinoma lines.";
RL   Cancer Res. 49:5167-5175(1989).
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).