ID   BL-36
AC   CVCL_C146
SY   BL36; BL 36; BL 036; IARC/BL36; IARC/BL 36; IARC-BL36; IARC BL36; IARC BL 36
DR   Cosmic; 931098
DR   DSMZ; ACC-917
DR   DSMZCellDive; ACC-917
DR   Wikidata; Q54797147
RX   PubMed=2898508;
RX   PubMed=2985508;
RX   PubMed=3027441;
RX   PubMed=3905596;
RX   PubMed=3934070;
RX   PubMed=6231253;
RX   PubMed=6592381;
RX   PubMed=8382295;
RX   PubMed=9473234;
RX   PubMed=11793449;
RX   PubMed=11983026;
RX   PubMed=25787276;
CC   From: International Agency of Research on Cancer (IARC); Lyon; France.
CC   Population: Algerian.
CC   Virology: Contains a complete EBV genome (strain BL36) which has been sequenced (PubMed=25787276). Contains from 5 to 10 episomal copies of EBV (PubMed=8382295).
CC   Doubling time: ~24 hours (DSMZ=ACC-917).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone, jaw; UBERON=UBERON_0001708.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): DSMZ=ACC-917
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 8,13
ST   D16S539: 11,12
ST   D18S51: 15
ST   D19S433: 14
ST   D21S11: 29.2,33.2
ST   D2S1338: 17,23
ST   D3S1358: 15,18
ST   D5S818: 9,11
ST   D7S820: 11,12
ST   D8S1179: 12,14
ST   FGA: 21,22
ST   Penta D: 3,11
ST   Penta E: 13,17
ST   TH01: 7,9
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_M641 ! BL-42
OI   CVCL_M565 ! BL-43
OI   CVCL_M566 ! BL-44
OI   CVCL_IV23 ! IARC-174
SX   Female
AG   54Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 02-05-24; Version: 19
//
RX   PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677;
RA   Gregory C.D., Murray R.J., Edwards C.F., Rickinson A.B.;
RT   "Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in
RT   Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell
RT   escape from virus-specific T cell surveillance.";
RL   J. Exp. Med. 167:1811-1824(1988).
//
RX   PubMed=2985508; DOI=10.1002/ijc.2910350404;
RA   Rowe M., Rooney C.M., Rickinson A.B., Lenoir G.M., Rupani H.,
RA   Moss D.J., Stein H., Epstein M.A.;
RT   "Distinctions between endemic and sporadic forms of Epstein-Barr
RT   virus-positive Burkitt's lymphoma.";
RL   Int. J. Cancer 35:435-441(1985).
//
RX   PubMed=3027441; DOI=10.1093/jnci/78.2.235;
RA   Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M.,
RA   Manel A.-M., Vincent C., Bryon P.-A.;
RT   "B-cell maturation stages of Burkitt's lymphoma cell lines according
RT   to Epstein-Barr virus status and type of chromosome translocation.";
RL   J. Natl. Cancer Inst. 78:235-242(1987).
//
RX   PubMed=3905596;
RA   Favrot M.-C., Philip I., Philip T., Cabrillat H., Pinatel C.,
RA   Dore J.-F., Lenoir G.M.;
RT   "Immunophenotypic classification of 28 Burkitt cell lines with
RT   monoclonal antibodies and reagent selection for bone-marrow purging.";
RL   IARC Sci. Publ. 60:447-452(1985).
//
RX   PubMed=3934070;
RA   Lenoir G.M., Vuillaume M., Bonnardel C.;
RT   "The use of lymphomatous and lymphoblastoid cell lines in the study of
RT   Burkitt's lymphoma.";
RL   IARC Sci. Publ. 60:309-318(1985).
//
RX   PubMed=6231253; DOI=10.1002/ijc.2910330407;
RA   Ehlin-Henriksson B., Klein G.;
RT   "Distinction between Burkitt lymphoma subgroups by monoclonal
RT   antibodies: relationships between antigen expression and type of
RT   chromosomal translocation.";
RL   Int. J. Cancer 33:459-463(1984).
//
RX   PubMed=6592381; DOI=10.1093/jnci/73.4.841;
RA   Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F.,
RA   Lenoir G.M.;
RT   "Distinct reactivity of Burkitt's lymphoma cell lines with eight
RT   monoclonal antibodies correlated with the ethnic origin.";
RL   J. Natl. Cancer Inst. 73:841-847(1984).
//
RX   PubMed=8382295; DOI=10.1128/JVI.67.3.1292-1299.1993; PMCID=PMC237496;
RA   Delecluse H.-J., Bartnitzke S., Hammerschmidt W., Bullerdiek J.,
RA   Bornkamm G.-W.;
RT   "Episomal and integrated copies of Epstein-Barr virus coexist in
RT   Burkitt lymphoma cell lines.";
RL   J. Virol. 67:1292-1299(1993).
//
RX   PubMed=9473234; DOI=10.1182/blood.V91.5.1680;
RA   Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.;
RT   "p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a
RT   mRNA and protein expression in Burkitt's lymphoma.";
RL   Blood 91:1680-1687(1998).
//
RX   PubMed=11793449; DOI=10.1002/gcc.10022;
RA   Sobol H., Benziane A., Kerangueven F., Yin L., Noguchi T., Pauly S.,
RA   Eisinger F., Longy M., Romeo G., Lenoir G.M., Birnbaum D.;
RT   "Genome-wide search for loss of heterozygosity in Burkitt lymphoma
RT   cell lines.";
RL   Genes Chromosomes Cancer 33:217-224(2002).
//
RX   PubMed=11983026; DOI=10.1186/1475-2867-1-2; PMCID=PMC101226;
RA   Poirier F., Bourin P., Bladier D., Joubert-Caron R., Caron M.;
RT   "Effect of 5-azacytidine and galectin-1 on growth and differentiation
RT   of the human B lymphoma cell line BL36.";
RL   Cancer Cell Int. 1:2.1-2.12(2001).
//
RX   PubMed=25787276; DOI=10.1128/JVI.03614-14; PMCID=PMC4442510;
RA   Palser A.L., Grayson N.E., White R.E., Corton C., Correia S.,
RA   Ba Abdullah M.M., Watson S.J., Cotten M., Arrand J.R., Murray P.G.,
RA   Allday M.J., Rickinson A.B., Young L.S., Farrell P.J., Kellam P.;
RT   "Genome diversity of Epstein-Barr virus from multiple tumor types and
RT   normal infection.";
RL   J. Virol. 89:5222-5237(2015).
//