ID   MT-2CB1
AC   CVCL_C0YR
SY   MT-2CB; CB1; MT-2Rst
DR   Wikidata; Q114312325
RX   PubMed=16850164;
RX   PubMed=22608188;
RX   PubMed=32187573;
CC   Population: Japanese.
CC   Selected for resistance to: ChEBI; CHEBI:46664; Chrysotile asbestos.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
CC   Cell type: Regulatory T-cell; CL=CL_0000815.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2631 ! MT-2
SX   Male
AG   <1D
CA   Transformed cell line
DT   Created: 22-09-22; Last updated: 29-06-23; Version: 4
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RX   PubMed=16850164; DOI=10.1007/s10495-006-9235-4;
RA   Miura Y., Nishimura Y., Katsuyama H., Maeda M., Hayashi H., Dong M.-L.,
RA   Hyodoh F., Tomita M., Matsuo Y., Uesaka A., Kuribayashi K., Nakano T.,
RA   Kishimoto T., Otsuki T.;
RT   "Involvement of IL-10 and Bcl-2 in resistance against an
RT   asbestos-induced apoptosis of T cells.";
RL   Apoptosis 11:1825-1835(2006).
//
RX   PubMed=22608188; DOI=10.1016/j.scitotenv.2012.04.043;
RA   Maeda M., Yamamoto S., Chen Y., Kumagai-Takei N., Hayashi H.,
RA   Matsuzaki H., Lee S., Hatayama T., Miyahara N., Katoh M.,
RA   Hiratsuka J.-i., Nishimura Y., Otsuki T.;
RT   "Resistance to asbestos-induced apoptosis with continuous exposure to
RT   crocidolite on a human T cell.";
RL   Sci. Total Environ. 429:174-182(2012).
//
RX   PubMed=32187573; DOI=10.1016/j.envint.2020.105654;
RA   Yamamoto S., Lee S., Matsuzaki H., Kumagai-Takei N., Yoshitome K.,
RA   Sada N., Shimizu Y., Ito T., Nishimura Y., Otsuki T.;
RT   "Enhanced expression of nicotinamide nucleotide transhydrogenase (NNT)
RT   and its role in a human T cell line continuously exposed to
RT   asbestos.";
RL   Environ. Int. 138:105654.1-105654.13(2020).
//