Cellosaurus logo
expasy logo

Cellosaurus MT-2CB1 (CVCL_C0YR)

[Text version]
Cell line name MT-2CB1
Synonyms MT-2CB; CB1; MT-2Rst
Accession CVCL_C0YR
Resource Identification Initiative To cite this cell line use: MT-2CB1 (RRID:CVCL_C0YR)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:46664; Chrysotile asbestos.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Cell type: Regulatory T-cell; CL=CL_0000815.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2631 (MT-2)
Sex of cell Male
Age at sampling <1D
Category Transformed cell line
Publications

PubMed=16850164; DOI=10.1007/s10495-006-9235-4
Miura Y., Nishimura Y., Katsuyama H., Maeda M., Hayashi H., Dong M.-L., Hyodoh F., Tomita M., Matsuo Y., Uesaka A., Kuribayashi K., Nakano T., Kishimoto T., Otsuki T.
Involvement of IL-10 and Bcl-2 in resistance against an asbestos-induced apoptosis of T cells.
Apoptosis 11:1825-1835(2006)

PubMed=22608188; DOI=10.1016/j.scitotenv.2012.04.043
Maeda M., Yamamoto S., Chen Y., Kumagai-Takei N., Hayashi H., Matsuzaki H., Lee S., Hatayama T., Miyahara N., Katoh M., Hiratsuka J.-i., Nishimura Y., Otsuki T.
Resistance to asbestos-induced apoptosis with continuous exposure to crocidolite on a human T cell.
Sci. Total Environ. 429:174-182(2012)

PubMed=32187573; DOI=10.1016/j.envint.2020.105654
Yamamoto S., Lee S., Matsuzaki H., Kumagai-Takei N., Yoshitome K., Sada N., Shimizu Y., Ito T., Nishimura Y., Otsuki T.
Enhanced expression of nicotinamide nucleotide transhydrogenase (NNT) and its role in a human T cell line continuously exposed to asbestos.
Environ. Int. 138:105654.1-105654.13(2020)

Cross-references
Encyclopedic resources Wikidata; Q114312325
Entry history
Entry creation22-Sep-2022
Last entry update29-Jun-2023
Version number4