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Cellosaurus B'SYS CHO hERG-Duo (CVCL_C0XV)

[Text version]
Cell line name B'SYS CHO hERG-Duo
Synonyms CHO hERG DUO
Accession CVCL_C0XV
Resource Identification Initiative To cite this cell line use: B'SYS CHO hERG-Duo (RRID:CVCL_C0XV)
Comments Characteristics: KCNH2 was transfected twice.
Genetic integration: Method=Transfection; Gene=HGNC; 6251; KCNH2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://www.bsys.ch/media/cho_herg-duo_2016.pdf
Publications

PubMed=25228880; DOI=10.3389/fphar.2014.00203; PMCID=PMC4151236
Danker T., Moller C.
Early identification of hERG liability in drug discovery programs by automated patch clamp.
Front. Pharmacol. 5:203.1-203.11(2014)

Cross-references
Encyclopedic resources Wikidata; Q114310645
Entry history
Entry creation22-Sep-2022
Last entry update10-Sep-2024
Version number7