Cellosaurus cell line BEL-A RHAG KO (CVCL

Cellosaurus BEL-A RHAG KO (CVCL_C0XF)

Cross-references
Cell line name	BEL-A RHAG KO
Synonyms	RhAG KO BEL-A
Accession	CVCL_C0XF
Resource Identification Initiative	To cite this cell line use: BEL-A RHAG KO (RRID:CVCL_C0XF)
Comments	Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10006; RHAG. Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. Cell type: Mononuclear cell of bone marrow; CL=CL_0010004.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_C0X7 (BEL-A2 clone 79)
Sex of cell	Sex unspecified
Age at sampling	Adult
Category	Transformed cell line
Publications	PubMed=29700043; DOI=10.15252/emmm.201708454; PMCID=PMC5991592 Hawksworth J.S., Satchwell T.J., Meinders M., Daniels D.E., Regan F., Thornton N.M., Wilson M.C., Dobbe J.G.G., Streekstra G.J., Trakarnsanga K., Heesom K.J., Anstee D.J., Frayne J., Toye A.M. Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing. EMBO Mol. Med. 10:e8454.1-e8454.11(2018) CLPUB00710 Hawksworth J.S. CRISPR-Cas9 gene editing in an immortalized erythroid cell line for production of engineered red blood cells. Thesis PhD (2019); University of Bristol; Bristol; United Kingdom
Encyclopedic resources	Wikidata; Q114310737
Entry history
Entry creation	22-Sep-2022
Last entry update	10-Apr-2025
Version number	8