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Cellosaurus BNI-VS-52 (CVCL_C0X4)

[Text version]
Cell line name BNI-VS-52
Accession CVCL_C0X4
Resource Identification Initiative To cite this cell line use: BNI-VS-52 (RRID:CVCL_C0X4)
Comments Population: Chinese.
Characteristics: Established from the PDX-NF2-VS-04 xenograft.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Peripheral nervous system, vestibular nerve; UBERON=UBERON_0003723.
Cell type: Schwann cell; CL=CL_0002573.
Sequence variations
  • Mutation; HGNC; HGNC:7773; NF2; Simple; c.808_809ins; Zygosity=Unspecified (PubMed=35394061).
Disease Neurofibromatosis type 2 (NCIt: C3274)
Vestibular schwannoma (NCIt: C3276)
Neurofibromatosis type 2 (ORDO: Orphanet_637)
Vestibular schwannoma (ORDO: Orphanet_252175)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): PubMed=35394061

Markers:
AmelogeninX,Y
CSF1PO9,11
D1S165615,17
D2S133820
D3S135816,17
D5S8189,13
D6S104311,18
D7S82011
D8S117913,15
D12S39118,20
D13S3179,10
D16S5399,10
D18S5114,15
D19S43313,16.2
D21S1130,31
FGA20,23
Penta D12,13
Penta E8,17
TH017,9
TPOX8,11
vWA16,18

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Publications

PubMed=35394061; DOI=10.1002/path.5908
Zhao F., Chen Y., Li S.-W., Zhang J., Zhang S., Zhao X.-B., Yang Z.-J., Wang B., He Q.-Y., Wang L.-M., Xu L., Liu P.-N.
Novel patient-derived xenograft and cell line models for therapeutic screening in NF2-associated schwannoma.
J. Pathol. 257:620-634(2022)

Cross-references
Encyclopedic resources Wikidata; Q114310761
Gene expression databases GEO; GSM5460963
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number5