ID   ImGNC
AC   CVCL_C0WR
SY   Immortalized Giant Nevi Cells
DR   Wikidata; Q114311737
RX   PubMed=35218152;
CC   Population: Chinese.
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=35218152).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Arm, skin, dermis; UBERON=UBERON_0002427+UBERON_0002067.
DI   NCIt; C4234; Giant congenital nevus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   7Y
CA   Transformed cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=35218152; DOI=10.1111/pcmr.13033;
RA   Yu Q.-X., Aimaier R., Chung M.-H., Cui X.-W., Li Y.-H., Wang Z.-C.,
RA   Li Q.-F.;
RT   "Establishment and characterization of an immortalized human giant
RT   congenital melanocytic nevi cell line.";
RL   Pigment Cell Melanoma Res. 35:356-368(2022).
//