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Cellosaurus GWH04 (CVCL_C0W3)

[Text version]
Cell line name GWH04
Synonyms GWH 04; Fu
Accession CVCL_C0W3
Resource Identification Initiative To cite this cell line use: GWH04 (RRID:CVCL_C0W3)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C202163.
Population: Chinese.
Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809.
Sequence variations
  • Mutation; HGNC; 1100; BRCA1; Simple; p.Glu1038Gly (c.3113A>G); ClinVar=VCV000041815; Zygosity=Unspecified (PubMed=36169178).
  • Mutation; HGNC; 3430; ERBB2; Simple; p.Ser423Gly (c.1267A>G); ClinVar=VCV001398791; Zygosity=Unspecified (PubMed=36169178).
  • Mutation; HGNC; 7127; MLH1; Simple; p.Val384Asp (c.1151T>A); ClinVar=VCV000041632; Zygosity=Unspecified (PubMed=36169178).
  • Mutation; HGNC; 7765; NF1; Simple; p.Ter640Argext (c.1918T>C); Zygosity=Unspecified (PubMed=36169178).
  • Mutation; HGNC; 8803; PDGFRA; Simple; p.Ser478Pro (c.1432T>C); ClinVar=VCV000041794; Zygosity=Unspecified (PubMed=36169178).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Tyr315Ter (c.945T>A); ClinVar=VCV000234509; Zygosity=Unspecified (PubMed=36169178).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=36169178).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr205Cys (c.614A>G); ClinVar=VCV000376681; Zygosity=Unspecified (PubMed=36169178).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): PubMed=36169178

Markers:
AmelogeninX
CSF1PO12
D1S165615
D2S133824
D3S135815,16
D5S81812,13
D6S104311,19
D7S82011,12
D8S117912,13
D12S39122,23
D13S3179
D16S53910,12
D19S43314
D21S1130
FGA22,23
Penta D9,15
Penta E12,18
TH017,9
TPOX8,9
vWA14,17

Run an STR similarity search on this cell line
Web pages http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3825
Publications

Patent=CN114214281A
Cheng F.-L., Wan X.-Y., Mao F., Wang B.-F., Guo D.-S.
Human glioblastoma cell line GWH04 and culture method and application thereof.
Patent number CN114214281A, 22-Mar-2022

PubMed=36169178; DOI=10.3892/ijo.2022.5429
Cheng F.-L., Wan X.-Y., Wang B.-F., Li Y.-W., Peng P., Xu S.-P., Han C., Mao F., Guo D.-S.
Establishment and characteristics of GWH04, a new primary human glioblastoma cell line.
Int. J. Oncol. 61:139.1-139.14(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0W3
CCRID; 4201PAT-CCTCC01832
Encyclopedic resources Wikidata; Q114311552
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5