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Cellosaurus AME-HPV (CVCL_C0W1)

[Text version]
Cell line name AME-HPV
Accession CVCL_C0W1
Resource Identification Initiative To cite this cell line use: AME-HPV (RRID:CVCL_C0W1)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Bone, jaw, mandible; UBERON=UBERON_0001684.
Cell type: Ameloblast; CL=CL_0000059.
Disease Follicular ameloblastoma (NCIt: C27397)
Ameloblastoma (ORDO: Orphanet_314419)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0W0 (AME-1 [Human ameloblastoma])
Sex of cell Female
Age at sampling 44Y
Category Transformed cell line
Publications

PubMed=25099616; DOI=10.1007/s13277-014-2401-3
da Rosa M.R.P., Falcao A.S.C., Fuzii H.T., da Silva Kataoka M.S., Ribeiro A.L.R., Boccardo E., de Siqueira A.S., Jaeger R.G., de Jesus Viana Pinheiro J., de Melo Alves Junior S.
EGFR signaling downstream of EGF regulates migration, invasion, and MMP secretion of immortalized cells derived from human ameloblastoma.
Tumor Biol. 35:11107-11120(2014)

PubMed=34060687; DOI=10.1111/odi.13930
de Souza Cruz E.L., Loureiro F.J.A., da Costa da Silva A.L., Ramos R.T.J., da Silva Kataoka M.S., de Jesus Viana Pinheiro J., de Melo Alves Junior S.
Gene expression in cell lines from human ameloblastoma immortalized using hTERT and HPV16-E6/E7.
Oral Dis. 28:2230-2238(2022)

Cross-references
Encyclopedic resources Wikidata; Q114310625
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number7