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Cellosaurus HEK293T ALKBH5/FTO DKO (CVCL_C0U1)

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Cell line name HEK293T ALKBH5/FTO DKO
Synonyms HEK293T deltaFTO deltaALKBH5; HEK293T dALKBH5dFTO
Accession CVCL_C0U1
Resource Identification Initiative To cite this cell line use: HEK293T ALKBH5/FTO DKO (RRID:CVCL_C0U1)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:25996; ALKBH5.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:24678; FTO.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=35516002; DOI=10.1016/j.dib.2022.108187; PMCID=PMC9062317
Smolin E.A., Buyan A.I., Lyabin D.N., Kulakovskiy I.V., Eliseeva I.A.
RNA-Seq data of ALKBH5 and FTO double knockout HEK293T human cells.
Data Brief 42:108187.1-108187.8(2022)

Cross-references
Encyclopedic resources Wikidata; Q112929696
Gene expression databases GEO; GSM5936930
GEO; GSM5936931
GEO; GSM5936932
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7