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Cellosaurus HEK293 MUT-KO clone 2 (CVCL_C0TZ)

[Text version]
Cell line name HEK293 MUT-KO clone 2
Accession CVCL_C0TZ
Resource Identification Initiative To cite this cell line use: HEK293 MUT-KO clone 2 (RRID:CVCL_C0TZ)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7526; MMUT.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Omics: Deep quantitative proteome analysis.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=32679819; DOI=10.3390/ijms21144998; PMCID=PMC7403994
Costanzo M., Caterino M., Cevenini A., Jung V., Chhuon C., Lipecka J., Fedele R., Guerrera I.C., Ruoppolo M.
Proteomics reveals that methylmalonyl-CoA mutase modulates cell architecture and increases susceptibility to stress.
Int. J. Mol. Sci. 21:4998.1-4998.28(2020)

PubMed=33195772; DOI=10.1016/j.dib.2020.106453; PMCID=PMC7644733
Costanzo M., Caterino M., Cevenini A., Jung V., Chhuon C., Lipecka J., Fedele R., Guerrera I.C., Ruoppolo M.
Dataset of a comparative proteomics experiment in a methylmalonyl-CoA mutase knockout HEK 293 cell model.
Data Brief 33:106453.1-106453.5(2020)

Cross-references
Encyclopedic resources Wikidata; Q112929669
Proteomic databases PRIDE; PXD017977
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7