ID   ACTOne GRM2
AC   CVCL_C0ST
DR   Wikidata; Q112929158
WW   http://www.codexbiosolutions.com/wp-content/uploads/cb-80300-262.pdf
CC   Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions).
CC   Genetic integration: Method=Transfection/transduction; Gene=RGD; 2367; Cnga2 (Note=With p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4594; GRM2.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:10941; SLC1A3.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C0RX ! HEK293-CNG-Slc1a3
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 19-12-24; Version: 6
//