ID   PC12-FR
AC   CVCL_C0PX
SY   PC12-Fast Responding; PC12-251; PC12 clone 251
DR   Wikidata; Q112930281
RX   PubMed=6303817;
RX   PubMed=6577005;
RX   PubMed=8900203;
RX   PubMed=9856988;
CC   Characteristics: Established after 3 passages by subcutaneous injection of the parent cell line into Deaconess rats.
CC   Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
CC   Breed/subspecies: NEDH.
DI   NCIt; C121568; Rat adrenal gland pheochromocytoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_0481 ! PC12
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 29-06-23; Version: 5
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RX   PubMed=6303817; DOI=10.1016/S0014-4827(83)80019-6;
RA   Heumann R., Kachel V., Thoenen H.;
RT   "Relationship between NGF-mediated volume increase and 'priming
RT   effect' in fast and slow reacting clones of PC12 pheochromocytoma
RT   cells. Role of cAMP.";
RL   Exp. Cell Res. 145:179-190(1983).
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RX   PubMed=6577005; DOI=10.1016/S0021-9258(17)44421-8;
RA   Lee R.W.H., Huttner W.B.;
RT   "Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their
RT   sulfation by a tyrosylprotein sulfotransferase.";
RL   J. Biol. Chem. 258:11326-11334(1983).
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RX   PubMed=8900203; DOI=10.1074/jbc.271.43.27116;
RA   Corradi N., Borgonovo B., Clementi E., Bassetti M., Racchetti G.,
RA   Consalez G.G., Huttner W.B., Meldolesi J., Rosa P.;
RT   "Overall lack of regulated secretion in a PC12 variant cell clone.";
RL   J. Biol. Chem. 271:27116-27124(1996).
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RX   PubMed=9856988; DOI=10.1074/jbc.273.52.34683;
RA   Borgonovo B., Racchetti G., Malosio M.L., Benfante R., Podini P.,
RA   Rosa P., Meldolesi J.;
RT   "Neurosecretion competence, an independently regulated trait of the
RT   neurosecretory cell phenotype.";
RL   J. Biol. Chem. 273:34683-34686(1998).
//