Cellosaurus PC12-27 (CVCL_C0PV)
Cell line name | PC12-27 | |
---|---|---|
Synonyms | PC 12-27; PC12 clone 27 | |
Accession | CVCL_C0PV | |
Resource Identification Initiative | To cite this cell line use: PC12-27 (RRID:CVCL_C0PV) | |
Comments | Characteristics: Fully incompetent for both branches of regulated secretion, those of dense granules and synaptic-like microvesicles, possibly because of the impairment of a general expression control system that appears to operate independently of neuroendocrine cell differentiation (PubMed=8900203). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369. | |
Disease | Rat adrenal gland pheochromocytoma (NCIt: C121568) | |
Species of origin | Rattus norvegicus (Rat)
(NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS:0000603. | |
Hierarchy | Parent: CVCL_0481 (PC12) Children:
| |
Sex of cell | Male | |
Age at sampling | Age unspecified | |
Category | Cancer cell line | |
Publications | PubMed=1657914; DOI=10.1016/S0021-9258(18)54903-6 PubMed=12106430; DOI=10.1111/j.1460-9568.1992.tb00121.x PubMed=8900203; DOI=10.1074/jbc.271.43.27116 PubMed=9856988; DOI=10.1074/jbc.273.52.34683 PubMed=9933147; DOI=10.1007/PL00005319 PubMed=10517799; DOI=10.1111/j.1469-7793.1999.t01-1-00043.x; PMCID=PMC2269568 | |
Cross-references | ||
Cell line databases/resources | TOKU-E; 3553 | |
Encyclopedic resources | Wikidata; Q112930276 | |
Entry history | ||
Entry creation | 23-Jun-2022 | |
Last entry update | 10-Sep-2024 | |
Version number | 6 |