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Cellosaurus CBIGi001-A-3 (CVCL_C0K1)

[Text version]
Cell line name CBIGi001-A-3
Synonyms PINK1-KO/PRKN-KO; AIW002-02/PINK1-KO/PRKN-KO; PINK1-KO/PRKN-KO/AIW002-02; Parkin_PINK1-KO/AIW002-02
Accession CVCL_C0K1
Resource Identification Initiative To cite this cell line use: CBIGi001-A-3 (RRID:CVCL_C0K1)
Comments From: Clinical Biospecimen Imaging and Genetic (C-BIG) Repository, Montreal Neurological Institute, McGill University; Montreal; Canada.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 14581; PINK1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 8607; PRKN.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0JZ (CBIGi001-A-1)
Sex of cell Male
Age at sampling 37Y
Category Induced pluripotent stem cell
Web pages https://cbigr-open.loris.ca/c-big_ipsc_catalog_May2022.pdf
Publications

PubMed=35561458; DOI=10.1016/j.scr.2022.102806
Chen C.X.-Q., You Z.-P., Abdian N., Sirois J., Shlaifer I., Tabatabaei M., Boivin M.-N., Gaborieau L., Karamchandani J., Beitel L.K., Fon E.A., Durcan T.M.
Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing.
Stem Cell Res. 62:102806-102806(2022)

Cross-references
Cell line databases/resources hPSCreg; CBIGi001-A-3
Biological sample resources BioSamples; SAMEA12866580
Encyclopedic resources Wikidata; Q112929369
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4