ID   HEK293 NDUSF2 KO
AC   CVCL_C0D2
SY   HEK293deltaNDUFS2; HEK293deltandufs2
DR   CancerTools; 156497
DR   Wikidata; Q112929670
DR   Ximbio; 156497
RX   Patent=WO2021067415A1;
RX   PubMed=33744462;
CC   Group: Patented cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 7708; NDUFS2.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 29-06-23; Version: 5
//
RX   Patent=WO2021067415A1;
RA   Bandara A.B., Brown D.A.;
RT   "NDUFS2 subunit knockout human cell line.";
RL   Patent number WO2021067415A1, 08-Apr-2021.
//
RX   PubMed=33744462; DOI=10.1016/j.mito.2021.03.003;
RA   Bandara A.B., Drake J.C., James C.C., Smyth J.W., Brown D.A.;
RT   "Complex I protein NDUFS2 is vital for growth, ROS generation,
RT   membrane integrity, apoptosis, and mitochondrial energetics.";
RL   Mitochondrion 58:160-168(2021).
//