ID   UPCI-SCC-182
AC   CVCL_C060
SY   UPCI:SCC182; SCC-182; SCC182
DR   cancercelllines; CVCL_C060
DR   DSMZ; ACC-887
DR   DSMZCellDive; ACC-887
DR   IARC_TP53; 18368
DR   Wikidata; Q54991689
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=24142626;
CC   Population: Caucasian.
CC   Doubling time: ~60-80 hours, ~100 hours (Note=After recovery from liquid nitrogen freezing) (DSMZ=ACC-887).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu294Ter (c.880G>T); ClinVar=VCV000379471; Zygosity=Unspecified (PubMed=12872257).
CC   Derived from site: In situ; Oral cavity, retromolar trigone; UBERON=UBERON_0012376.
ST   Source(s): DSMZ=ACC-887
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 13
ST   D18S51: 13,19
ST   D19S433: 14,15
ST   D21S11: 31
ST   D2S1338: 24,25
ST   D3S1358: 17
ST   D5S818: 13
ST   D7S820: 11
ST   D8S1179: 13,14
ST   FGA: 21,28
ST   Penta D: 13
ST   Penta E: 15,17
ST   TH01: 7
ST   TPOX: 8,9
ST   vWA: 17,18
DI   NCIt; C8172; Retromolar trigone squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   71Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 16
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977;
RA   Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W.,
RA   Vlad A., Gollin S.M.;
RT   "Upregulation of the ATR-CHEK1 pathway in oral squamous cell
RT   carcinomas.";
RL   Genes Chromosomes Cancer 53:25-37(2014).
//