ID   UPCI-SCC-125
AC   CVCL_C054
SY   UPCI:SCC125; UPCISCC125; SCC125
DR   cancercelllines; CVCL_C054
DR   DSMZ; ACC-885
DR   DSMZCellDive; ACC-885
DR   IARC_TP53; 18365
DR   Wikidata; Q54991675
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
RX   PubMed=28196595;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: ~40-50 hours (DSMZ=ACC-885).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Pro151His (c.452C>A); ClinVar=VCV000376639; Zygosity=Unspecified (PubMed=12872257).
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004102.
ST   Source(s): DSMZ
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 11,13
ST   D16S539: 12,13
ST   D18S51: 13
ST   D19S433: 13
ST   D21S11: 28,30
ST   D2S1338: 19,24
ST   D3S1358: 15,16
ST   D5S818: 11,13
ST   D7S820: 8,11
ST   D8S1179: 10,13
ST   FGA: 21,25
ST   Penta D: 10,13
ST   Penta E: 7,18
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 15,16
DI   NCIt; C170774; Alveolar ridge squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   78Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 16
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//