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Cellosaurus UPCI-SCC-084 (CVCL_C047)

[Text version]
Cell line name UPCI-SCC-084
Synonyms UPCI:SCC084; SCC084
Accession CVCL_C047
Resource Identification Initiative To cite this cell line use: UPCI-SCC-084 (RRID:CVCL_C047)
Comments Population: Caucasian.
Doubling time: ~22 hours (DSMZ=ACC-878).
Derived from site: In situ; Oral cavity, retromolar trigone; UBERON=UBERON_0012376.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220fs*27 (c.655delC) (p.P219Lfs); Zygosity=Unspecified (PubMed=12872257).
Disease Retromolar trigone squamous cell carcinoma (NCIt: C8172)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WH59 (SCC084/R)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-878

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817
D3S135816
D5S81813
D7S8209,12
D8S117913,16
D13S31711
D16S5399,13
D18S5114
D19S43314
D21S1128
FGA20
Penta D9
Penta E11,15
TH016
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=12872257; DOI=10.1002/humu.10248
Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M., Ishwad C.S., Jarvik J.W.
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065
Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W., Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977
Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W., Vlad A., Gollin S.M.
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

PubMed=27045798; DOI=10.1038/srep23932; PMCID=PMC4820705
Ghosh R.D., Ghuwalewala S., Das P., Mandloi S., Alam S.K., Chakraborty J., Sarkar S., Chakrabarti S., Panda C.K., Roychoudhury S.
MicroRNA profiling of cisplatin-resistant oral squamous cell carcinoma cell lines enriched with cancer-stem-cell-like and epithelial-mesenchymal transition-type features.
Sci. Rep. 6:23932-23932(2016)

Cross-references
Cell line collections (Providers) DSMZ; ACC-878
Cell line databases/resources DSMZCellDive; ACC-878
Encyclopedic resources Wikidata; Q54991654
Polymorphism and mutation databases Cosmic; 1969497
IARC_TP53; 18357
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number17