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Cellosaurus UPCI-SCC-077 (CVCL_C043)

[Text version]
Cell line name UPCI-SCC-077
Synonyms UPCI:SCC077; SCC077
Accession CVCL_C043
Resource Identification Initiative To cite this cell line use: UPCI-SCC-077 (RRID:CVCL_C043)
Comments Population: Caucasian.
Doubling time: ~60-70 hours (DSMZ=ACC-866).
Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln317Hisfs*28 (c.951del); Zygosity=Unspecified (PubMed=12872257).
Disease Floor of mouth squamous cell carcinoma (NCIt: C4041)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-866

Markers:
AmelogeninX,Y
CSF1PO10
D2S133817
D3S135814
D5S8189
D7S8208
D8S117914,15
D13S31711
D16S53911,13
D18S5113
D19S43312,14
D21S1127,29
FGA21
Penta D13
Penta E7,13
TH019.3
TPOX11
vWA17,18

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Publications

PubMed=12872257; DOI=10.1002/humu.10248
Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M., Ishwad C.S., Jarvik J.W.
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065
Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W., Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977
Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W., Vlad A., Gollin S.M.
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

Cross-references
Cell line collections (Providers) DSMZ; ACC-866
Cell line databases/resources DSMZCellDive; ACC-866
Encyclopedic resources Wikidata; Q54991608
Polymorphism and mutation databases IARC_TP53; 18356
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number14