ID   ES-R1 CAG-S-hRXRalpha
AC   CVCL_BW94
DR   Wikidata; Q54832459
RX   PubMed=20382891;
CC   Characteristics: The transfected construct consist of a ubiquitous CAGGS (hybrid chicken beta actin and cytomegalovirus) promoter, a loxP-STOP-loxP (LSL) cassette and the Myc-FLAG-tagged NR/CoR cDNA followed by a polyadenylation signal. The contruct is silent and the transfected gene can be conditionally overexpressed after cre recombinase mediated activation.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:10477; RXRA.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
CC   Breed/subspecies: 129X1/SvJ x 129S1/Sv-Oca2+Tyr+KitlSl-J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_2167 ! ES-R1
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 13-07-16; Last updated: 19-12-24; Version: 10
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RX   PubMed=20382891; DOI=10.1210/me.2010-0068; PMCID=PMC2875802;
RA   Wu S.-P., Lee D.-K., DeMayo F.J., Tsai S.Y., Tsai M.-J.;
RT   "Generation of ES cells for conditional expression of nuclear
RT   receptors and coregulators in vivo.";
RL   Mol. Endocrinol. 24:1297-1304(2010).
//