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Cellosaurus Abcam A-549 IQGAP1 KO (CVCL_B9KW)

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Cell line name Abcam A-549 IQGAP1 KO
Synonyms Human IQGAP1 knockout A549
Accession CVCL_B9KW
Resource Identification Initiative To cite this cell line use: Abcam A-549 IQGAP1 KO (RRID:CVCL_B9KW)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:6110; IQGAP1.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Abcam; ab288840
Cell line databases/resources cancercelllines; CVCL_B9KW
Encyclopedic resources Wikidata; Q112927394
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6