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Cellosaurus UBT-5 (CVCL_B972)

[Text version]
Cell line name UBT-5
Accession CVCL_B972
Resource Identification Initiative To cite this cell line use: UBT-5 (RRID:CVCL_B972)
Comments Population: Japanese and Korean.
Genetic integration: Method=Transduction; Gene=HGNC; 1066; BMI1.
Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6F32 (H4-1 [Human bone marrow])
Sex of cell Female
Age at sampling 91Y
Category Telomerase immortalized cell line
Publications

PubMed=15293342; DOI=10.1002/jgm.583
Takeda Y., Mori T., Imabayashi H., Kiyono T., Gojo S., Miyoshi S., Hida N., Ita M., Segawa K., Ogawa S., Sakamoto M., Nakamura S., Umezawa A.
Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation?
J. Gene Med. 6:833-845(2004)

PubMed=15923633; DOI=10.1128/mcb.25.12.5183-5195.2005; PMCID=PMC1140572
Mori T., Kiyono T., Imabayashi H., Takeda Y., Tsuchiya K., Miyoshi S., Makino H., Matsumoto K., Saito H., Ogawa S., Sakamoto M., Hata J.-i., Umezawa A.
Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.
Mol. Cell. Biol. 25:5183-5195(2005)

Cross-references
Encyclopedic resources Wikidata; Q54973900
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number11