Cellosaurus logo
expasy logo

Cellosaurus WCMC-37 (CVCL_B919)

[Text version]
Cell line name WCMC-37
Synonyms WCMC 37; WCMC37; WMC 37
Accession CVCL_B919
Resource Identification Initiative To cite this cell line use: WCMC-37 (RRID:CVCL_B919)
Comments From: Weill Cornell Medical College; New York; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0211.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:3775; FMR1; Repeat_expansion; CGG[142-450]; Zygosity=Hemizygous (PubMed=24289922).
Disease Fragile X syndrome (NCIt: C84717)
Fragile X syndrome (ORDO: Orphanet_908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=24289922; DOI=10.1016/j.molcel.2013.10.029; PMCID=PMC3920742
Gerhardt J., Tomishima M.J., Zaninovic N., Colak D., Yan Z., Zhan Q.-S., Rosenwaks Z., Jaffrey S.R., Schildkraut C.L.
The DNA replication program is altered at the FMR1 locus in fragile X embryonic stem cells.
Mol. Cell 53:19-31(2014)

PubMed=27690107; DOI=10.3390/genes7100077; PMCID=PMC5083916
Mor-Shaked H., Eiges R.
Modeling fragile X syndrome using human pluripotent stem cells.
Genes (Basel) 7:77.1-77.19(2016)

Cross-references
Cell line databases/resources NIHhESC; NIHhESC-13-0211
Encyclopedic resources Wikidata; Q54993669
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number21