Cellosaurus cell line Abcam Hep-G2 SLC7A11 KO (CVCL

Cross-references
Cell line name	Abcam Hep-G2 SLC7A11 KO
Synonyms	Human SLC7A11 (xCT) knockout Hep G2
Accession	CVCL_B7V7
Resource Identification Initiative	To cite this cell line use: Abcam Hep-G2 SLC7A11 KO (RRID:CVCL_B7V7)
Comments	Population: Caucasian. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11059; SLC7A11. Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease	Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0027 (Hep-G2)
Sex of cell	Male
Age at sampling	15Y
Category	Cancer cell line
Cell line collections (Providers)	Abcam; ab275411
Cell line databases/resources	cancercelllines; CVCL_B7V7
Encyclopedic resources	Wikidata; Q112928349
Entry history
Entry creation	23-Jun-2022
Last entry update	19-Dec-2024
Version number	6