ID   e-hStr-2
AC   CVCL_B7UE
DR   Wikidata; Q112929499
RX   PubMed=29520052;
CC   Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
CC   Karyotypic information: 44<2n>XY,der(5)t(5;14)(p12;q11),-13,-21 (PubMed=29520052).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3527; EZH2.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7545; MYB.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:103262; Yap1.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Stromal cell of bone marrow; CL=CL_0010001.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B7UD ! e-hStr-1
OI   CVCL_B7UF ! e-hStr-3
OI   CVCL_B7UG ! e-hStr-4
OI   CVCL_B7UH ! e-hStr-5
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 10-04-25; Version: 7
//
RX   PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645;
RA   Lipps C., Klein F., Wahlicht T., Seiffert V., Butueva M., Zauers J.,
RA   Truschel T., Luckner M., Koster M., MacLeod R.A.F., Pezoldt J., Huhn J.,
RA   Yuan Q.-G., Muller P.P., Kempf H., Zweigerdt R., Dittrich-Breiholz O.,
RA   Pufe T., Beckmann R., Drescher W., Riancho J.A., Sanudo C., Korff T.,
RA   Opalka B., Rebmann V., Gothert J.R., Alves P.M., Ott M., Schucht R.,
RA   Hauser H., Wirth D., May T.;
RT   "Expansion of functional personalized cells with specific transgene
RT   combinations.";
RL   Nat. Commun. 9:994.1-994.12(2018).
//