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Cellosaurus e-hStr-1 (CVCL_B7UD)

[Text version]
Cell line name e-hStr-1
Accession CVCL_B7UD
Resource Identification Initiative To cite this cell line use: e-hStr-1 (RRID:CVCL_B7UD)
Comments Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
Karyotypic information: 111<5n>XXXX,-X,del(X)(q25),del(1)(p22),i(21)(q10) (PubMed=29520052).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3527; EZH2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3796; FOS.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11195; SOX2.
Genetic integration: Method=Transduction; Gene=MGI; MGI:102811; Lmo2.
Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
Genetic integration: Method=Transduction; Gene=MGI; MGI:103262; Yap1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Stromal cell of bone marrow; CL=CL_0010001.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B7UE ! e-hStr-2
CVCL_B7UF ! e-hStr-3
CVCL_B7UG ! e-hStr-4
CVCL_B7UH ! e-hStr-5
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645
Lipps C., Klein F., Wahlicht T., Seiffert V., Butueva M., Zauers J., Truschel T., Luckner M., Koster M., MacLeod R.A.F., Pezoldt J., Huhn J., Yuan Q.-G., Muller P.P., Kempf H., Zweigerdt R., Dittrich-Breiholz O., Pufe T., Beckmann R., Drescher W., Riancho J.A., Sanudo C., Korff T., Opalka B., Rebmann V., Gothert J.R., Alves P.M., Ott M., Schucht R., Hauser H., Wirth D., May T.
Expansion of functional personalized cells with specific transgene combinations.
Nat. Commun. 9:994.1-994.12(2018)

Cross-references
Encyclopedic resources Wikidata; Q112929498
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number7