ID   e-hFib-3
AC   CVCL_B7U3
DR   Wikidata; Q112929477
RX   PubMed=29520052;
CC   Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (PubMed=29520052).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3527; EZH2.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:103262; Yap1.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:99187; Zfp42.
CC   Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Fibroblast of foreskin; CL=CL_1001608.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0266 ! FS-4 [Human foreskin]
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645;
RA   Lipps C., Klein F., Wahlicht T., Seiffert V., Butueva M., Zauers J.,
RA   Truschel T., Luckner M., Koster M., MacLeod R.A.F., Pezoldt J., Huhn J.,
RA   Yuan Q.-G., Muller P.P., Kempf H., Zweigerdt R., Dittrich-Breiholz O.,
RA   Pufe T., Beckmann R., Drescher W., Riancho J.A., Sanudo C., Korff T.,
RA   Opalka B., Rebmann V., Gothert J.R., Alves P.M., Ott M., Schucht R.,
RA   Hauser H., Wirth D., May T.;
RT   "Expansion of functional personalized cells with specific transgene
RT   combinations.";
RL   Nat. Commun. 9:994.1-994.12(2018).
//