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Cellosaurus e-hFib-1 (CVCL_B7U1)

[Text version]
Cell line name e-hFib-1
Accession CVCL_B7U1
Resource Identification Initiative To cite this cell line use: e-hFib-1 (RRID:CVCL_B7U1)
Comments Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
Karyotypic information: 78<3n>XXYY,+1,add(2)(p24),-3,+6,+7,+del(8)(q21),+9,add(9)(p2?),+10,der(10)t(5;10)(q15:p15),+11,+18,der(19)t(11;19)(q13;p13),+20,+21,+22,+2mar (PubMed=29520052).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3527; EZH2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:667; RHOA.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0266 (FS-4 [Human foreskin])
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645
Lipps C., Klein F., Wahlicht T., Seiffert V., Butueva M., Zauers J., Truschel T., Luckner M., Koster M., MacLeod R.A.F., Pezoldt J., Huhn J., Yuan Q.-G., Muller P.P., Kempf H., Zweigerdt R., Dittrich-Breiholz O., Pufe T., Beckmann R., Drescher W., Riancho J.A., Sanudo C., Korff T., Opalka B., Rebmann V., Gothert J.R., Alves P.M., Ott M., Schucht R., Hauser H., Wirth D., May T.
Expansion of functional personalized cells with specific transgene combinations.
Nat. Commun. 9:994.1-994.12(2018)

Cross-references
Encyclopedic resources Wikidata; Q112929475
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number7