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Cellosaurus e-hDFib2 (CVCL_B7TZ)

[Text version]
Cell line name e-hDFib2
Accession CVCL_B7TZ
Resource Identification Initiative To cite this cell line use: e-hDFib2 (RRID:CVCL_B7TZ)
Comments Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
Karyotypic information: 44<2n>XY,der(2)t(2;4)(p24;p11),-4,-13,add(14)(p11) (PubMed=29520052).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B7TY ! CI-huFIB
CVCL_B7U0 ! e-hDFib3
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645
Lipps C., Klein F., Wahlicht T., Seiffert V., Butueva M., Zauers J., Truschel T., Luckner M., Koster M., MacLeod R.A.F., Pezoldt J., Huhn J., Yuan Q.-G., Muller P.P., Kempf H., Zweigerdt R., Dittrich-Breiholz O., Pufe T., Beckmann R., Drescher W., Riancho J.A., Sanudo C., Korff T., Opalka B., Rebmann V., Gothert J.R., Alves P.M., Ott M., Schucht R., Hauser H., Wirth D., May T.
Expansion of functional personalized cells with specific transgene combinations.
Nat. Commun. 9:994.1-994.12(2018)

Cross-references
Encyclopedic resources Wikidata; Q112929471
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number7