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Cellosaurus Scid.adh.2C2 (CVCL_B7SD)

[Text version]
Cell line name Scid.adh.2C2
Synonyms adh.2C2
Accession CVCL_B7SD
Resource Identification Initiative To cite this cell line use: Scid.adh.2C2 (RRID:CVCL_B7SD)
Comments Characteristics: Overexpresses PU.1 (Spi1).
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; MGI; MGI:104779; Prkdc; Simple; p.Tyr4046Ter (c.12138T>A) (Prkdc(scid)); Zygosity=Homozygous (from inference of genetic background of Scid mice).
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C.B.-17-scid (CB17/Icr-Prkdcscid/IcrIcoCrl).
Hierarchy Parent: CVCL_B7SC (Scid.adh)
Category Cancer cell line
Publications

PubMed=15882585; DOI=10.1016/j.ydbio.2005.01.027
Dionne C.J., Tse K.Y., Weiss A.H., Franco C.B., Wiest D.L., Anderson M.K., Rothenberg E.V.
Subversion of T lineage commitment by PU.1 in a clonal cell line system.
Dev. Biol. 280:448-466(2005)

Cross-references
Encyclopedic resources Wikidata; Q112930348
Entry history
Entry creation23-Jun-2022
Last entry update02-May-2024
Version number6