ID   SW620-Lv-T7 R3E6
AC   CVCL_B7Q7
DR   cancercelllines; CVCL_B7Q7
DR   Wikidata; Q112930449
RX   PubMed=33592218;
CC   Population: Caucasian.
CC   Characteristics: Transduced with a lentiviral vector pLv-T7 containing T7-RNAP gene, puroR and mCherry.
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P00573; Bacteriophage T7 DNA-directed RNA polymerase.
CC   Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0547 ! SW620
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=33592218; DOI=10.1016/j.jviromet.2021.114099;
RA   Yeong M.Y., Cheow P.-S., Abdullah S., Song A.A.-L., Lei-Rossmann J.,
RA   Tan T.-K., Yusoff K., Chia S.-L.;
RT   "Development of a T7 RNA polymerase expressing cell line using
RT   lentivirus vectors for the recovery of recombinant Newcastle disease
RT   virus.";
RL   J. Virol. Methods 291:114099.1-114099.9(2021).
//