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Cellosaurus SW620-Lv-T7 R3C5 (CVCL_B7Q6)

[Text version]
Cell line name SW620-Lv-T7 R3C5
Accession CVCL_B7Q6
Resource Identification Initiative To cite this cell line use: SW620-Lv-T7 R3C5 (RRID:CVCL_B7Q6)
Comments Population: Caucasian.
Characteristics: Transduced with a lentiviral vector pLv-T7 containing T7-RNAP gene, puroR and mCherry.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00573; Bacteriophage T7 DNA-directed RNA polymerase.
Genetic integration: Method=Transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=33592218; DOI=10.1016/j.jviromet.2021.114099
Yeong M.Y., Cheow P.-S., Abdullah S., Song A.A.-L., Lei-Rossmann J., Tan T.-K., Yusoff K., Chia S.-L.
Development of a T7 RNA polymerase expressing cell line using lentivirus vectors for the recovery of recombinant Newcastle disease virus.
J. Virol. Methods 291:114099.1-114099.9(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7Q6
Encyclopedic resources Wikidata; Q112930448
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7