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Cellosaurus PC9/TS1 (CVCL_B7N9)

[Text version]
Cell line name PC9/TS1
Accession CVCL_B7N9
Resource Identification Initiative To cite this cell line use: PC9/TS1 (RRID:CVCL_B7N9)
Comments Population: Chinese; Han and Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 12441; TYMS.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; 3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B260 (PC-9)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
Publications

PubMed=21487406; DOI=10.1038/bjc.2011.129; PMCID=PMC3101907
Takezawa K., Okamoto I., Okamoto W., Takeda M., Sakai K., Tsukioka S., Kuwata K., Yamaguchi H., Nishio K., Nakagawa K.
Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer.
Br. J. Cancer 104:1594-1601(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7N9
Encyclopedic resources Wikidata; Q112930291
Entry history
Entry creation23-Jun-2022
Last entry update10-Sep-2024
Version number6