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Cellosaurus H1299/TS2 (CVCL_B7N8)

[Text version]
Cell line name H1299/TS2
Accession CVCL_B7N8
Resource Identification Initiative To cite this cell line use: H1299/TS2 (RRID:CVCL_B7N8)
Comments Population: Caucasian.
Karyotypic information: Has lost chromosome Y (from parent cell line).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:12441; TYMS.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0060 (NCI-H1299)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=21487406; DOI=10.1038/bjc.2011.129; PMCID=PMC3101907
Takezawa K., Okamoto I., Okamoto W., Takeda M., Sakai K., Tsukioka S., Kuwata K., Yamaguchi H., Nishio K., Nakagawa K.
Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer.
Br. J. Cancer 104:1594-1601(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7N8
Encyclopedic resources Wikidata; Q112929639
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7