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Cellosaurus MC-BR-BTY-0006 (CVCL_B7JZ)

[Text version]
Cell line name MC-BR-BTY-0006
Accession CVCL_B7JZ
Resource Identification Initiative To cite this cell line use: MC-BR-BTY-0006 (RRID:CVCL_B7JZ)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Characteristics: Established from a nude mouse xenograft (PubMed=34145270).
Doubling time: 48-72 hours (PubMed=34145270).
Omics: Deep exome analysis.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Gln2829Leu (c.8486A>C); Zygosity=Homozygous (PubMed=34145270).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg174His (c.521G>A); Zygosity=Homozygous (PubMed=34145270).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=34145270

Markers:
AmelogeninX
CSF1PO12
D3S135815
D5S81814
D7S8209,15
D8S117911,13
D13S31711
D16S53911
D18S5116
D21S1130,31
FGA22
Penta D13,15
Penta E12
TH017
TPOX9
vWA17

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Publications

PubMed=34145270; DOI=10.1038/s41523-021-00285-x; PMCID=PMC8213738
Zhuang Y.-X., Grainger J.M., Vedell P.T., Yu J., Moyer A.M., Gao H.-Y., Fan X.-Y., Qin S.-S., Liu D., Kalari K.R., Goetz M.P., Boughey J.C., Weinshilboum R.M., Wang L.-W.
Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX).
NPJ Breast Cancer 7:79.1-79.12(2021)

Cross-references
Encyclopedic resources Wikidata; Q112930074
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7