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Cellosaurus PEO4-iPSC-OSKM-05 (CVCL_B7JJ)

[Text version]
Cell line name PEO4-iPSC-OSKM-05
Accession CVCL_B7JJ
Resource Identification Initiative To cite this cell line use: PEO4-iPSC-OSKM-05 (RRID:CVCL_B7JJ)
Comments Population: Caucasian.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Tyr1655Tyr (c.4965C>T) (5193C>T); ClinVar=VCV001657967; Zygosity=Hemizygous; Note=De novo mutation that cancels the c.4965C>G (5193C>G) mutation in the patient (from parent cell line).
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Arg160Trp (c.478A>T); ClinVar=VCV000412204; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly244Asp (c.731G>A); ClinVar=VCV000372785; Zygosity=Homozygous (from parent cell line).
Disease BRCA2-associated hereditary breast and ovarian cancer syndrome (NCIt: C36101)
Ovarian cystadenocarcinoma (NCIt: C5228)
Hereditary breast and ovarian cancer syndrome (ORDO: Orphanet_145)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2690 (PEO4)
Sex of cell Female
Age at sampling Age unspecified
Category Induced pluripotent stem cell
Publications

PubMed=34343671; DOI=10.1016/j.biocel.2021.106051
Bindhya S., Sidhanth C., Krishnapriya S., Garg M., Ganesan T.S.
Development and in vitro characterisation of an induced pluripotent stem cell model of ovarian cancer.
Int. J. Biochem. Cell Biol. 138:106051.1-106051.15(2021)

Cross-references
Encyclopedic resources Wikidata; Q114312651
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6