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Cellosaurus HindIIIG-1 (CVCL_B7J1)

[Text version]
Cell line name HindIIIG-1
Accession CVCL_B7J1
Resource Identification Initiative To cite this cell line use: HindIIIG-1 (RRID:CVCL_B7J1)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03246; Adenovirus 5 E1B 19 kDa protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A/E1B).
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=24626185; DOI=10.4161/cc.28402; PMCID=PMC4050140
Chitikova Z.V., Gordeev S.A., Bykova T.V., Zubova S.G., Pospelov V.A., Pospelova T.V.
Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers.
Cell Cycle 13:1424-1439(2014)

DOI=10.1134/S1990519X2104009X
Chitikova Z.V., Yartseva N.M., Bykova T.V., Zubova S.G., Kochetkova E.Y., Pospelov V.A., Pospelova T.V.
Establishment of HindIIIG-1 cell line, obtained after irradiation of HindIIIG cells resistant to apoptosis, characterizes by genomic instability, altered DNA repair mechanisms and activation of autophagy.
Cell Tissue Biol. 15:370-380(2021)

Cross-references
Encyclopedic resources Wikidata; Q112929729
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6