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Cellosaurus RB355 Eto-R (CVCL_B7II)

[Text version]
Cell line name RB355 Eto-R
Synonyms RB-355 etoposide-resistant; RB-355 Etop
Accession CVCL_B7II
Resource Identification Initiative To cite this cell line use: RB355 Eto-R (RRID:CVCL_B7II)
Comments Problematic cell line: Contaminated. Parent cell line (RB355) has been shown to be a Y-79 derivative.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_S611 (RB355)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line
Publications

PubMed=29192327; DOI=10.3892/or.2017.6100; PMCID=PMC5783599
Busch M.A., Papior D., Stephan H., Dunker N.
Characterization of etoposide- and cisplatin-chemoresistant retinoblastoma cell lines.
Oncol. Rep. 39:160-172(2018)

Cross-references
Encyclopedic resources Wikidata; Q114312771
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number5