Cellosaurus cell line PC-B-148CA (CVCL

Cellosaurus PC-B-148CA (CVCL_B7I2)

[Text version]

Cell line name

PC-B-148CA

Accession

CVCL_B7I2

Resource Identification Initiative

To cite this cell line use: PC-B-148CA (RRID:CVCL_B7I2)

Comments

Group: Triple negative breast cancer (TNBC) cell line.
Population: Southeast Asian; Thai.
Doubling time: 155.7 +- 5.2 hours (PubMed=34651665).
Karyotypic information: 47-58 chromosomes with loss of both copies of chr X (PubMed=34651665).
Derived from site: In situ; Breast; UBERON=UBERON_0000310.

Sequence variations

Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Thr3033Asnfs*11 (c.9097dupA); ClinVar=VCV000038208; Zygosity=Heterozygous (PubMed=34651665).
Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000040468; Zygosity=Heterozygous (PubMed=34651665).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (PubMed=34651665).

Disease

Breast carcinoma (NCIt: C4872)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

50Y

Category

Cancer cell line

STR profile

Source(s): PubMed=34651665

Markers:

CSF1PO	13
D2S1338	20
D3S1358	16,17
D5S818	12,13
D7S820	8,11
D8S1179	14,17
D13S317	8
D16S539	11
D18S51	11,12
D19S433	13.2,14.2
D21S11	29,31
FGA	18
TH01	6,9
TPOX	9,12
vWA	18,19

Publications

PubMed=34651665; DOI=10.3892/or.2021.8205; PMCID=PMC8548790
Thongchot S., Jamjuntra P., Prasopsiri J., Thuwajit P., Sawasdee N., Poungvarin N., Warnnissorn M., Sa-nguanraksa D., O-Charoenrat P., Yenchitsomanus P.-T., Thuwajit C.
Establishment and characterization of novel highly aggressive HER2-positive and triple-negative breast cancer cell lines.
Oncol. Rep. 46:254.1-254.13(2021)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_B7I2

Encyclopedic resources

Wikidata; Q112930253

Entry history

Entry creation

23-Jun-2022

Last entry update

19-Dec-2024

Version number