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Cellosaurus WCRC-25 (CVCL_B7HJ)

[Text version]
Cell line name WCRC-25
Synonyms WCRC0025-76M
Accession CVCL_B7HJ
Resource Identification Initiative To cite this cell line use: WCRC-25 (RRID:CVCL_B7HJ)
Comments Population: Caucasian.
Characteristics: ER-positive, PR-negative and ERBB2-negative.
Doubling time: ~5 days (CelloPub=CLPUB00696).
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1748; CDH1; Zygosity=Heterozygous (CelloPub=CLPUB00696).
  • Mutation; HGNC; HGNC:1748; CDH1; Simple; p.Gln706Ter (c.2116C>T); Zygosity=Heterozygous (CelloPub=CLPUB00696).
Disease Invasive breast lobular carcinoma (NCIt: C7950)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Publications

CLPUB00696
Bossart E.A.
Investigation of EMT-like phenotypes in established and novel model systems of invasive lobular breast carcinoma.
Thesis PhD (2018); University of Pittsburgh; Pittsburgh; USA

DOI=10.1158/1538-7445.SABCS17-P5-06-03
Kota K., Bossart E.A., Basudan A., Minteer T., Meier C., Brown D., Gurda G.T., Miller L., Dabbs D.J., Lee A.V., Puhalla S.L., Jankowitz R.C., McAuliffe P.F., Lucas P.C., Oesterreich S.
Generation and characterization of a novel invasive lobular breast carcinoma cell line WCRC-25.
Cancer Res. 78 Suppl. 4:P5.06.03-P5.06.03(2018)

DOI=10.1158/1538-7445.SABCS21-P5-12-03
Elangovan A., Bossart E.A., Basudan A., Tasdemir N., Shah O.S., Ding K., Meier C., Heim T., Miller L., Liu T.-T., Puhalla S.L., Gurda G.T., Lucas P.C., McAuliffe P.F., Atkinson J.M., Lee A.V., Oesterreich S.
WCRC-25: a novel luminal invasive lobular carcinoma cell line model.
Cancer Res. 82 Suppl. 4:P5.12.03-P5.12.03(2022)

Cross-references
Encyclopedic resources Wikidata; Q112930563
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6