Cellosaurus cell line A6/C1 (CVCL

Cellosaurus A6/C1 (CVCL_B7ED)

Cross-references
Cell line name	A6/C1
Synonyms	A6-C1; A6C1
Accession	CVCL_B7ED
Resource Identification Initiative	To cite this cell line use: A6/C1 (RRID:CVCL_B7ED)
Comments	Group: Amphibian cell line. Characteristics: Selected for its high transepithelial resistance and for its responsiveness to aldosterone and antidiuretic hormone (PubMed=8392584). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin	Xenopus laevis (African clawed frog) (NCBI Taxonomy: 8355)
Hierarchy	Parent: CVCL_F714 (A6-2F3)
Sex of cell	Male
Age at sampling	Adult stage
Category	Spontaneously immortalized cell line
Publications	PubMed=3032984; DOI=10.1083/jcb.104.5.1231; PMCID=PMC2114475 Verrey F., Schaerer E., Zoerkler P., Paccolat M.-P., Geering K., Kraehenbuhl J.-P., Rossier B.C. Regulation by aldosterone of Na+,K+-ATPase mRNAs, protein synthesis, and sodium transport in cultured kidney cells. J. Cell Biol. 104:1231-1237(1987) PubMed=8392584; DOI=10.1007/BF00232021 Verrey F., Digicaylioglu M., Bolliger U. Polarized membrane movements in A6 kidney cells are regulated by aldosterone and vasopressin/vasotocin. J. Membr. Biol. 133:213-226(1993) PubMed=8189433; DOI=10.1007/BF00211070 Verrey F. Antidiuretic hormone action in A6 cells: effect on apical Cl and Na conductances and synergism with aldosterone for NaCl reabsorption. J. Membr. Biol. 138:65-76(1994)
Encyclopedic resources	Wikidata; Q112927067
Entry history
Entry creation	23-Jun-2022
Last entry update	05-Oct-2023
Version number	5