Cellosaurus cell line PMAC5 (CVCL

Cellosaurus PMAC5 (CVCL_B7B4)

[Text version]

Cell line name

PMAC5

Synonyms

Peter MacCallum Anal Cancer 5

Accession

CVCL_B7B4

Resource Identification Initiative

To cite this cell line use: PMAC5 (RRID:CVCL_B7B4)

Comments

Doubling time: 24 hours (PubMed=34663790).
Omics: Deep exome analysis.
Derived from site: In situ; Anal canal; UBERON=UBERON_0000159.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (PubMed=34663790).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly279Trp (c.835G>T); Zygosity=Unspecified (PubMed=34663790).

Disease

Anal squamous cell carcinoma (NCIt: C9161)
Squamous cell carcinoma of the anal canal (ORDO: Orphanet_424019)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

51Y

Category

Cancer cell line

STR profile

Source(s): PubMed=34663790

Markers:

Amelogenin	X
CSF1PO	11
D5S818	12
D7S820	9,13
D13S317	13
D16S539	11,12
D21S11	30,31.2
TH01	6,9.3
TPOX	8,11
vWA	16,17

Publications

PubMed=34663790; DOI=10.1038/s41419-021-04141-5; PMCID=PMC8523722
Guerra G.R., Kong J.C., Millen R.M., Read M., Liu D.S., Roth S., Sampurno S., Sia J., Bernardi M.-P., Chittleborough T.J., Behrenbruch C.C., Teh J., Xu H.-L., Haynes N.M., Yu J., Lupat R., Hawkes D., Di Costanzo N., Tothill R.W., Mitchell C., Ngan S.Y., Heriot A.G., Ramsay R.G., Phillips W.A.
Molecular and genomic characterisation of a panel of human anal cancer cell lines.
Cell Death Dis. 12:959-959(2021)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_B7B4

Encyclopedic resources

Wikidata; Q112129531

Sequence databases

EGA; EGAD00001007001

Entry history

Entry creation

17-Mar-2022

Last entry update

19-Dec-2024

Version number