Cellosaurus cell line PMAC1 (CVCL

Cellosaurus PMAC1 (CVCL_B7B0)

[Text version]

Cell line name

PMAC1

Synonyms

Peter MacCallum Anal Cancer 1

Accession

CVCL_B7B0

Resource Identification Initiative

To cite this cell line use: PMAC1 (RRID:CVCL_B7B0)

Comments

Doubling time: 47 hours (PubMed=34663790).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Deep exome analysis.
Derived from site: In situ; Anal canal; UBERON=UBERON_0000159.

Sequence variations

Mutation; HGNC; HGNC:13726; KMT2C; Simple; p.Gln88Ter (c.262C>T); Zygosity=Unspecified (PubMed=34663790).
Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu726Lys (c.2176G>A); ClinVar=VCV000376476; Zygosity=Unspecified (PubMed=34663790).

Disease

Anal squamous cell carcinoma (NCIt: C9161)
Squamous cell carcinoma of the anal canal (ORDO: Orphanet_424019)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

58Y

Category

Cancer cell line

STR profile

Source(s): PubMed=34663790

Markers:

Amelogenin	X
CSF1PO	11,12
D5S818	11
D7S820	10,12
D13S317	8
D16S539	9,13
D21S11	30.2,32
TH01	7
TPOX	8,11
vWA	14,17

Publications

PubMed=34663790; DOI=10.1038/s41419-021-04141-5; PMCID=PMC8523722
Guerra G.R., Kong J.C., Millen R.M., Read M., Liu D.S., Roth S., Sampurno S., Sia J., Bernardi M.-P., Chittleborough T.J., Behrenbruch C.C., Teh J., Xu H.-L., Haynes N.M., Yu J., Lupat R., Hawkes D., Di Costanzo N., Tothill R.W., Mitchell C., Ngan S.Y., Heriot A.G., Ramsay R.G., Phillips W.A.
Molecular and genomic characterisation of a panel of human anal cancer cell lines.
Cell Death Dis. 12:959-959(2021)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_B7B0

Encyclopedic resources

Wikidata; Q112129526

Sequence databases

EGA; EGAD00001007001

Entry history

Entry creation

17-Mar-2022

Last entry update

19-Dec-2024

Version number