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Cellosaurus HOMC-D4 (CVCL_B7AZ)

[Text version]
Cell line name HOMC-D4
Accession CVCL_B7AZ
Resource Identification Initiative To cite this cell line use: HOMC-D4 (RRID:CVCL_B7AZ)
Comments Population: Japanese.
Karyotypic information: 45,XY,-13,-22,+mar [55%] (PubMed=34663305).
Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Greater omentum mesothelium; UBERON=UBERON_0005670.
Cell type: Mesothelial cell; CL=CL_0000077.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_B7AX ! HOMC-A4
CVCL_B7AY ! HOMC-B1
Sex of cell Male
Age at sampling 51Y
Category Transformed cell line
STR profile Source(s): PubMed=34663305

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135816,18
D5S81810,11
D7S82011,12
D8S117913,15
D13S31712
D16S5399,12
D18S5113,16
D21S1129,30
FGA21,22
Penta D10
Penta E12,19
TH016,9
TPOX8,9
vWA14

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Publications

PubMed=34663305; DOI=10.1186/s12935-021-02248-5; PMCID=PMC8525006
Sato T., Nakanishi H., Akao K., Okuda M., Mukai S., Kiyono T., Sekido Y.
Three newly established immortalized mesothelial cell lines exhibit morphological phenotypes corresponding to malignant mesothelioma epithelioid, intermediate, and sarcomatoid types, respectively.
Cancer Cell Int. 21:546.1-546.11(2021)

Cross-references
Encyclopedic resources Wikidata; Q111733446
Gene expression databases GEO; GSM3684946
Entry history
Entry creation17-Mar-2022
Last entry update10-Sep-2024
Version number6