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Cellosaurus WIL2-S-Luc2 (CVCL_B7AE)

[Text version]
Cell line name WIL2-S-Luc2
Accession CVCL_B7AE
Resource Identification Initiative To cite this cell line use: WIL2-S-Luc2 (RRID:CVCL_B7AE)
Comments Population: Caucasian.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-8885-LUC2).
Doubling time: 15.5 hours (ATCC=CRL-8885-LUC2).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Spleen; UBERON=UBERON_0002106.
Sequence variations
  • Mutation; HGNC; 11272; SPTA1; Simple; p.Ser1163Ala (c.3487T>G); ClinVar=VCV000258929; Zygosity=Homozygous (from parent cell line).
Disease Hereditary spherocytosis (NCIt: C97074)
Hereditary spherocytosis (ORDO: Orphanet_822)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3809 (WIL2 S)
Sex of cell Male
Age at sampling 5Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-8885-LUC2

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81812,13
D7S8209,11
D13S31711
D16S53911,12
TH018,9.3
TPOX8,11
vWA17,20

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Cross-references
Cell line collections (Providers) ATCC; CRL-8885-LUC2
Encyclopedic resources Wikidata; Q123033916
Entry history
Entry creation05-Oct-2023
Last entry update10-Sep-2024
Version number4