DR   Wikidata; Q111733518
RX   PubMed=21419799;
RX   PubMed=22987579;
CC   Problematic cell line: Contaminated. Shown to be a Caki-1 derivative (PubMed=22987579). The parent cell line was originally thought to originate from a 28 year old male patient with HIV-1 negative Kaposi sarcoma.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Leu98Pro (c.293T>C); ClinVar=VCV001502192; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Derived from metastatic site: Skin.
ST   Source(s): PubMed=22987579
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 12
ST   D5S818: 11
ST   D7S820: 8,12
ST   TH01: 6,8
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9569 ! SLK
SX   Male
AG   49Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 21-03-23; Version: 4
RX   PubMed=21419799; DOI=10.1016/j.jviromet.2011.03.012;
RA   Myoung J., Ganem D.;
RT   "Generation of a doxycycline-inducible KSHV producer cell line of
RT   endothelial origin: maintenance of tight latency with efficient
RT   reactivation upon induction.";
RL   J. Virol. Methods 174:12-21(2011).
RX   PubMed=22987579; DOI=10.1002/ijc.27849;
RA   Sturzl M., Gaus D., Dirks W.G., Ganem D., Jochmann R.;
RT   "Kaposi's sarcoma-derived cell line SLK is not of endothelial origin,
RT   but is a contaminant from a known renal carcinoma cell line.";
RL   Int. J. Cancer 132:1954-1958(2013).